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These chemicals are generated from injured or stressed cells in response to ROS formation and operate as signaling factors to recruit and activate immune cells, sustaining inflammation (Albano et al., 2022)

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However, one study found that certain tumor cells were still able to survive and proliferate after GPX4 deletion

Later, this question was further explored by Mutvei et al

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Comprehensive metabolic profiling of inflammation indicated key roles of glycerophospholipid and arginine metabolism in coronary artery disease